Contrary to popular belief just one egg a day helps to combat tuberculosis (TB). The study was conducted by a research team from Colorado State University. Their findings are published in the Journal of Clinical Pathology and viral Biology.
According to the World Health Organization tuberculosis (TB) is the fifth leading cause of cancer-related deaths per 100000 people in the world. There are around 1. 8 billion people living with tuberculosis worldwide. These people comprise either primary or secondary TB. People diagnosed with TB suffer from a dramatically higher relapse rate than those who arent diagnosed with this disease. This discrepancy however often results in an inadequate response to medications.
Professor Manoj Dravidhya senior author of the study said We started out by doing a trial in mild patients with tertiary TB. Three to four years ago we started seeing an increased level of Treg in these patients. We then added a single egg a day.
The study included the trial patients living in the Downtown Kalimantan tuberculosis treatment centre a tertiary delousing facility and referral hospital for higher-risk groups.
Ten patients were gradually treated with either an 8 or a 16-egg a day said Dravidhya. The study was conducted for up to six months. Up to 14 days were spent in an 8-egg a day trial. After three months they were exposed to TB virus for 6 months (100 days).
Exposure to TB infection was assessed during clinical examinations as well as by the patients themselves. Patients were monitored for their clinical condition and required a minimum of 8 hours of hospitalisation each day due to severe fatigue and temperature rash.
The findings identified a significantly greater reduction of the primary TB burden (49. 6 percent) compared with the first round of therapy (10. 7 percent) and between the 16-egg therapy (32. 2 percent) and 24-egg therapy (16. 7 percent).
At end of treatment the 16-egg therapy group had around two-thirds as much of the TB burden as the 36-egg therapy group.
The results were replicated in another centre where 48 volunteers were infected with TB while continuing treatment with the same number of pills for a period of eight months. The effects of egg a day were similar.
Scharitha Mishra the first author of the study said This trial is one of the few epidemiological studies undertaken where subjects were followed on a day-to-day basis and where we were provided with an opportunity to compare the effectiveness of each dose of treatment.
The single dose of treatment and the 16-egg therapy was given jointly for 12 weeks and was expected to help the patients get the desired results.
Treg was higher in the protein of spermatozoa which can become all of the important proteins involved in the TB-fighting cells. We saw no difference in spermatory Treg compared to either 1 or 2 doses given simultaneously. This meant that the single dose of antimicrobial therapy was less effective than the combination said Dravidhya.
The studys results can be important for designing TB therapy in the future. No difference was found between the two doses for the strength of the TB-fighting cells the type of TB detected or the amount of time spent for secondary testing he said.
With using single-dose drug treatment the bacteria were not detected in the testes. As a countermeasure only the vaccine was found via the testes.
We are really impressed with these findings because they could help us identify more targets to richen school-based treatment courses for TB in a healthier growing population said the studys lead author Manish K. Agarwal MD from the University of Colorado Anschutz Medical Campus.
Eggs were used with the aim of using egg purchase and bottle packaging for sale at reasonable rates. The title of the study was Eggs for TB Augmenting a Meal at Home.