A team of researchers from the Netherlands the UK and Singapore has developed atlas of blood cells with unique blood flow identity based on their molecular signatures. The project was conducted by scientists at the Netherlands Institute of Medical Image Computing (NIUMC) and Universidade Mendoza (UNM) in partnership with the institution of Teatro de Cincia de RN Cuba and the University of Nova Punto (UNP). It is published in Nature Biomedical Engineering.

Your blood cell is like a highway or a transportation network connecting your blood vessels to the rest of your body. But thanks to genetic engineering you can control how close your arteries and veins are to each other so that they can sense blood flow and so that your blood no longer flows through one side as well as the other. This artificial procedure can cause long-term abnormalities such as a build-up of dense proteins in your blood vessels. This build-up results in nerve damage that can lead to a paralytic disease.

Identifying unique blood flow pattern.

The team developed unique blood flow characteristics which were then analyzed by artificial intelligence to identify the approximate blood flow patterns of normal and diseased hands at the finger level. It is a method for atlas or compendium of permanent characterised blood flow patterns. The computer system analyzed samples of the patients from Htel de Laval supported by the Immersive Experimental Human Factor 5 study at the University of Caen Vlieger-Hospital (UvH) using four different reference points with the use of a high-performance laser contrast agent (454 nm wavelength range i.e. about 635 nm down to 3. 8 nm).

Using this technique and intelligent blood flow analysis using off-the-shelf laptops a group of researchers from several European national research institutes was able to create atlas of all major blood cell types supported by peripheral blood vessels. The method uses COMPASS and Machine learning methods to identify specific distribution and blood flow patterns of different blood types overlaying the same sequence of blood input. COMPASS is a functional branch of the Artificial Intelligence used to generate quantitative functional networks connecting artificial intelligence with computers. It is not currently developed for biomedical projects.