UCLA researchers have identified an unknown chemical target within the enginate-encoded protein a protein that plays a critical role in driving the nitrogen-based cellular chemistry.

This discovery represents an important step in the development of a new enzyme in cell biology that could be used as a component of cell-based biosystems to control the activity of ATP synthase an enzyme that acts as the energy producer in cells and is considered an essential element in the cellular network.

AMP synthase function is essential to drive the energy production of genetic and other cells through utilization of phosphate co-activators and the enzymes major positive and oxidizing enzyme products. Understanding the sequence of this protein-encoding enzyme may help researchers seeking to develop further therapeutic strategies to inhibit AMP synthase activity.

This research was published in the Proceedings of the National Academy of Sciences (PNAS).