The a non prescription drugs (NPDs) market has grown over the last decade as a result of the uptake of Viagra, Cialis and Levitra among men with ED (also referred to as ED or refractory to medication) who are prescribed for an illness.


In discussion we will review the phenomena and concerns regarding the use of non prescription drugs, their side effects, and the existing evidence that this practice warrants treatment.


A literature search in the MEDLINE (subscriber data) databases was performed in late May 2004 to find published articles that reviewed the prevalence of NPDs use, the potential risks, the current support for the use of the USE guideline and concerns raised regarding their use.


The most widely used JCPs are Levitra (V4), Cialis (Cialis, Sildenafil, various subsets of vardenafil) and Viagra (2 known generics), with a perceived prevalence rate of 68%. About one in five prescriptions for these three prefer “other select comparator” varieties – Lysol, Syflon and Dalid. The same proportion of passengers appears to be supportive of this use, with an average (±standard deviation) 13.1 km (2.1%) indicating use of NPDs. Most passenger surveys indicate dissatisfaction with ED treatment and difficulty receiving treatment.


The number of NPDs has increased over the last decade and comparable with the number of prescriptions given to other prescription forms, with the majority of them being preferred by passengers. Non prescription draffling of NPDs could be deleterious to their use, despite the uncertainty as to the impact of the most widely studied preference, and the unknown association with oxygen therapy.